Thank you for your very interesting question. It is actually a question that needs more research, especially as there is growing evidence that there may be an inflammatory component to glaucoma. However, to date there is no evidence of NSAIDs causing or affecting the progression of glaucoma. There are some studies suggesting that the use of topical or oral NSAIDs may enhance the effect of eye-pressure lowering medications such as prostaglandin analogues (e.g., latanoprost). However, more work needs to be done to verify this finding and currently there is no recommendation concerning this type of treatment from the American Academy of Ophthalmology.