I am not certain what your doctor is referring to regarding pupil size and its relation to dry macular degeneration. There is no proven therapy to cure or reverse dry macular degeneration, but the AREDS vitamin formulation has been shown to decrease the risk of progression of high-risk dry age-related macular degeneration to the advanced form of the disease. You should ask your doctor more specifically about your eye pain. Eye pain can result from a variety of causes, including sinus problems, inflammation in or around the eye, surface irritation from the eye itself, or inflammation of the blood vessels around the eye. Your doctor should be able to address possible causes of your eye pain.