Evaluated for: Wet macular degeneration
How it works: Numerous studies have reported the benefits of laser photocoagulation therapy for the treatment of wet macular degeneration. While photocoagulation is beneficial for many patients, it is well known that many patients do not meet the guidelines to receive this form of treatment. Thus, scientists are actively searching for alternative treatment options. Radiation therapy is one such form of experimental treatment for wet macular degeneration. It involves the use of low-dose irradiation to inhibit the growth of abnormal blood vessels and subsequent scar formation. The rationale for the treatment is that radiation induces the regression of abnormal vessels that already exist and likely promotes the inactivation of cells responsible for the growth of other new vessels before they start to grow. This results in the reabsorption of fluid and blood, which reduces the risk for further leakage or bleeding. The exact mechanism or factors responsible for this inhibitory effect on vessel growth and scar formation are not known. However, several clinical studies report that patients who receive radiation therapy as a treatment for wet macular degeneration appear to benefit significantly, particularly those patients who do not meet the guidelines to receive other forms of treatment. The benefits of radiation treatment include stabilization and/or preservation of vision and prevention of progression to advanced stage macular degeneration.
Most common side effects: Macular scarring, subsequent abnormal vessel growth and/or hemorrhage may occur as a result of this treatment.
Miscellaneous: Clinical studies are presently underway to test a device called the TheraSight Ocular Brachytheraphy System which uses low energy x-rays for treating AMD. FDA approval will likely depend upon the outcome of these and other such studies.
A thoughtful evaluation must be performed by a physician before taking any medications, over-the-counter drugs, supplements, or herbs. The American Health Assistance Foundation does not endorse any of these medications, vitamins, or herbs. A qualified physician should make an informed decision based on each person's medical history and current prescriptions. The medication summaries provided do not include all of the information important for patient use and should not be used as a substitute for professional medical advice. The prescribing physician should be consulted concerning any questions that you have.
The information provided in this section of our website was obtained from the National Institutes of Health (NIH)/National Eye institute (NEI), the Food and Drug Administration (FDA), the National Library of Medicine, and research scientists specializing in macular degeneration.
Reviewed on 2/14/2008