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Grant Funding for Macular Degeneration Research

National Glaucoma Research - Current Award

Teri Belecky-Adams, Ph.D.

Trustees of Indiana University
Indianapolis, IN

Title: Bmp7 and glaucoma
Non-Technical Title: The role of growth factor Bmp7 in gliosis and ganglion cell survival

Duration: April 1, 2008 - March 31, 2010
Award Type: Standard
Award Amount: $100,000

Summary:

This study will focus on understanding the role of a growth factor, Bmp7, in both the increased survival of ganglion cells and the disruptive changes the glial cells undergo during glaucoma.

Details:

Glaucoma often involves a build up of fluid within the eye that creates pressure on the optic nerve, killing retinal ganglion cells, the cells that communicate with the rest of the brain. There are also disruptive changes to the glial cells in the optic nerve, cells that normally support the ganglion cells. This study will focus on understanding the role of a growth factor, Bmp7, in both the increased survival of ganglion cells and the disruptive changes the glial cells undergo during glaucoma. This may lead to novel glaucoma therapies to save ganglion cells and decrease disruptive changes to the glial cells.