Macular Degeneration Research - Current Award
|
Zhenglin Yang, M.D.
University of California, San Diego
La Jolla, CA
Title: Functional Study of HTRA1 and Age-related Macular Degeneration
Non-Technical Title: Etiology and Pathogenesis of Age-related Macular Degeneration
Duration: April 1, 2008 - March 31, 2010
Award Type: Standard
Award Amount: $100,000 |
Summary:
Identification and functional studies of the HTRA1, a gene that has substantial impact on the risk of AMD, may define key molecular pathways involved in its pathogenesis. The experiments will yield novel mechanistic insights relevant to the pathogenesis of both early and late AMD. This may lead to therapies directed at the underlying cause and pre-symptomatic diagnosis leading to earlier intervention. |
Details:
Identification and functional studies of the HTRA1, a gene that has substantial impact on the risk of AMD, may define key molecular pathways involved in its pathogenesis. The experiments will yield novel mechanistic insights relevant to the pathogenesis of both early and late AMD. This may lead to therapies directed at the underlying cause and pre-symptomatic diagnosis leading to earlier intervention.